Biomonitoring through the laboratory evaluation of a population exposed to ores

  • Silvia Eline Alfaia Lima Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Federal do Amapá (UNIFAP), Macapá, AP, Brasil / Instituto Nacional de Ciência e Tecnologia Forense (INCT), Porto Alegre, RS, Brasil
  • Amanda Furtado de Almeida Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Federal do Amapá (UNIFAP), Macapá, AP, Brasil / Instituto Nacional de Ciência e Tecnologia Forense (INCT), Porto Alegre, RS, Brasil
  • Roberto Messias Bezerra Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Federal do Amapá (UNIFAP), Macapá, AP, Brasil
  • Francinaldo Sarges Braga Curso de Farmácia, Universidade Federal do Amapá (UNIFAP), Macapá, AP, Brasil
  • Beatriz de Oliveira Azevedo Curso de Farmácia, Universidade Federal do Amapá (UNIFAP), Macapá, AP, Brasil
  • Wentony Mark Costa Milhomen Instituto Nacional de Ciência e Tecnologia Forense (INCT), Porto Alegre, RS, Brasil / Curso de Farmácia, Universidade Federal do Amapá (UNIFAP), Macapá, AP, Brasil
  • Alicia Karine Pereira da Silva Curso de Farmácia, Universidade Federal do Amapá (UNIFAP), Macapá, AP, Brasil
  • Maitê Amanajás Viana Curso de Farmácia, Universidade Federal do Amapá (UNIFAP), Macapá, AP, Brasil
  • Odirlei Santos Moreira Secretaria de Educação do Estado do Amapá (SEED), Macapá, AP, Brasil
  • Deyse de Souza Dantas Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Federal do Amapá (UNIFAP), Macapá, AP, Brasil
  • Madson Ralide Fonseca Gomes Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Federal do Amapá (UNIFAP), Macapá, AP, Brasil / Instituto Nacional de Ciência e Tecnologia Forense (INCT), Porto Alegre, RS, Brasil
Keywords: Water. Amazon. Laboratory. Metals. Ores. Toxic.

Abstract

The mineral exploration in the Amazon, has determined impacts for the environment and for the populations exposed to different agents of the production process. The extraction and the beneficiation developed in the state of Amapa left environmental damages and issues that influence the population´s health, such as contamination by metals. Researches have shown that some forms of metals are toxic; causing neurological and genetic complications. The present work considers the toxicological evaluation a fundamental prerequisite in the identification of potential damages to the health. Accordingly, the study´s objective is the investigating of the toxic effects through laboratory analysis in a population group of the Elesbao district in Santana-AP municipality exposed to residues of minerals and metals. In this way, the amount of metals in Elesbao´s water region was evaluated by spectrophotometer, hematological and biochemical tests were accomplished for laboratory evaluation. The paired t-test was applied for statistical evaluation with a significance of 5% (p <0.05). It was concluded that iron and manganese are present in high concentrations in the region water. Hematological and biochemical exams presented statistically relevant alterations. Significant differences in the morphology of the cells were detected by microscopic analysis. This study demonstrates the importance of the investigation of sources of metal exposure and preventing the elimination and minimization of the risks of adverse effects to excessive exposure to multiple metals.

Published
2020-05-14
Section
Research Article